- Dr. Hedman is the Founder and General Partner President of Orthopeutics, L.P., a Biotechnology Intellectual Property management company.
- Intralink Spine, Inc. was spun out of Orthopeutics in 2009 and is responsible for commercializing the Réjuve injectable medical device for the treatment of spinal disorders.
- Crosscoat Medical, LLC was recently spun out of Orthopeutics. Crosscoat Medical is responsible for commercializing all except spinal human applications of Orthopeutics multiply-patented core technologies.
- Equimedtech Limited (Ireland) is a licensee of Orthopeutics with the mission to commercialize an injectable treatment for horse upper airway breathing disorders, in particular dorsal displacement of the soft palate (DDSP).